When people detox you must always remember that you have to drink plenty of water! I recently got an email from someone who told me that they had severe abdominal cramping from using a detox drink. The suggestion I told her was to drink more water. Water will push the detox through your system faster, thereby affording you the benefits of the cleanse along. The idea is to cleanse, not to store the detox herbs in the body. The herbs and marine botanicals in some detox can cause some cramping. The answer for ANY detox is drink more water. If of course you are on medications, it is always advisable to consult your doctor to see if there are any contraindications between the detox ingredients and the medications you take. But always remember W-A-T-E-R, and at least 64 oz in total per day.